Article
Genotype-independent association between profound vitamin D deficiency and delayed sputum smear conversion in pulmonary tuberculosis.
BMC infectious diseases - 21 Jul 2015
Junaid Kashaf, Rehman Abdul, Saeed Tahir, Jolliffe David A, Wood Kristie, Martineau Adrian R
Abstract excerpt
BACKGROUND: Both vitamin D deficiency and genetic variants in the vitamin D receptor (VDR) have been reported to associate with delayed response to intensive-phase therapy for pulmonary tuberculosis. Studies investigating the influence of genetic variants in vitamin D binding protein (DBP) and vitamin D 25-hydroxylase (CYP2R1) on vitamin D status and response to antituberculous therapy are lacking. METHODS: We...
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