Article

Vitamin D binding protein gene polymorphisms and the risk of respiratory diseases: a meta-analysis and systematic review

2026-08-13

Abstract excerpt

Abstract Background Recent studies have found that VDBP gene polymorphism is closely related to the pathogenesis of some respiratory diseases. Rs7041 and rs4588 are two major single-nucleotide polymorphisms(SNPs) in the GC gene encoding VDBP. Different combinations of these variants give rise to three major haplotypic isoforms, GC*1F, GC*1S, and GC*2, which may influence pulmonary immune-inflammatory responses and...

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Literature Corpus work: b6b1d61a-1abe-5291-b93e-5e68a13fc98e
DOI: 10.1186/s12920-026-02443-1

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