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Article

Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis.

International journal of circumpolar health - 1 Jan 2015

Larcombe Linda, Mookherjee Neeloffer, Slater Joyce, Slivinski Caroline, Dantouze Joe, Singer Matthew, Whaley Chris, Denechezhe Lizette, Matyas Sara, Decter Kate, Turner-Brannen Emily, Ramsey Clare, Nickerson Peter, Orr Pamela

Abstract excerpt

BACKGROUND: Canadian First Nation populations have experienced endemic and epidemic tuberculosis (TB) for decades. Vitamin D-mediated induction of the host defence peptide LL-37 is known to enhance control of pathogens such as Mycobacterium tuberculosis. OBJECTIVE: Evaluate associations between serum levels of 25-hydroxy vitamin D (25(OH)D) and LL-37, in adult Dene First Nation participants (N = 34) and assess...

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Identifiers

PMID: 26294193
DOI: 10.3402/ijch.v74.28952
PMCID: PMC4543449

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VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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