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Article

Natural genetic diversity as a means to uncover stem cell regulatory pathways.

Annals of the New York Academy of Sciences - 1 Sept 2009

Van Zant Gary, Liang Ying

Abstract excerpt

Natural genetic diversity is a largely untapped reservoir for use in the discovery of stem cell regulatory pathways. Here we explore the means by which phenotypic diversity in mice can lead to the discovery of novel genes affecting stem cell regulation. We use as an example the discovery that latexin is a regulator of the natural size of the hematopoietic stem cell population in mice. The fact that it is a...

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Identifiers

PMID: 19796245
DOI: 10.1111/j.1749-6632.2009.04567.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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