Article
Uncommon and Challenging Phenotypes of High-Risk Human Papillomavirus-Associated Head and Neck Carcinomas Revealed by High-Throughput Studies.
Head and neck pathology - 22 Oct 2024
Tannenbaum Alex P, Lozar Taja, Lu Changxue, Schumacher Megan, Golfinos Athena, Dinh Huy Q, Taylor Natalie, Kimple Randall J, Yang David, Harari Paul M, Lambert Paul F, Lloyd Ricardo V, Hu Rong
Abstract excerpt
BACKGROUND: HPV- associated squamous cell carcinoma (SCC) is uncommon in non-oropharynx sites and not well characterized. This study aims to investigate uncommon phenotypes of HPV-associated head and neck carcinoma, the prevalence and morphologic spectrum of HPV-associated SCC in the oral cavity, larynx and hypopharynx. METHOD: P16 immunostaining and HPV E6/7 in situ hybridization (ISH) were performed on tissue...
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