Article
Usefulness of genotyping APC gene for individualizing management of patients with familial adenomatous polyposis.
International journal of clinical oncology - 1 Dec 2023
Mori Yoshiko, Ishida Hideyuki, Chika Noriyasu, Ito Tetsuya, Amano Kunihiko, Chikatani Kenichi, Takeuchi Yoji, Kono Mitsuhiro, Shichijo Satoki, Chino Akiko, Nagasaki Toshiya, Takao Akinari, Takao Misato, Nakamori Sakiko, Sasaki Kazuhito, Akagi Kiwamu, Yamaguchi Tatsuro, Tanakaya Kohji, Naohiro Tomita, Ajioka Yoichi
Abstract excerpt
BACKGROUND: Colorectal polyp burden is crucial for the management of patients with familial adenomatous polyposis (FAP). However, accurate evaluation of polyp burden is difficult to standardize. This study aimed to examine the possible utility of genotype-oriented management of colorectal neoplasms in patients with FAP. METHODS: Clinicopathological data from genetically proven patients with FAP was analyzed using...
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