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Article

Multipoint linkage analysis and heterogeneity testing in 20 X-linked retinitis pigmentosa families.

Genomics - 1 Oct 1990

Musarella M A, Anson-Cartwright L, Leal S M, Gilbert L D, Worton R G, Fishman G A, Ott J

Abstract excerpt

Using multipoint linkage analysis in 20 families segregating for X-linked retinitis pigmentosa (XLRP), the lod scores on a map of eight RFLP loci were obtained. Our results indicate that under the hypothesis of homogeneity the maximal multipoint lod score supports one disease locus located slightly distal to OTC at Xp21.1. Heterogeneity testing for two XLRP loci suggested that a second XLRP locus may be located...

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Identifiers

PMID: 1979051
DOI: 10.1016/0888-7543(90)90284-2
PMCID: PMC6174538

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OTC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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