Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Refined localization of the gene causing X-linked juvenile retinoschisis.

Genomics - 1 Mar 1991

Alitalo T, Kruse T A, de la Chapelle A

Abstract excerpt

Previous linkage studies in X-linked juvenile retinoschisis (RS) placed the gene between the loci DXS43 and DXS41 in the region Xp22.2-p22.1. Here we have extended our earlier studies by analyzing 31 RS families with the markers DXS16 (pSE3.2-L), DXS274, DXS92, and ZFX. Pairwise linkage analysis revealed significant linkage of the RS gene to all markers used; locus DXS274 (probe CRI-L1391) was tightly-linked to...

Topics

Chromosome Mapping
Finland
Genetic Linkage
Genetic Markers
Haplotypes
Humans
Mutation
Pedigree
Polymorphism, Genetic
Recombination, Genetic
Retinal Diseases
X Chromosome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2032721
DOI: 10.1016/0888-7543(91)90417-d

Genes

ZFX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2032721-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Refined localization of the gene causing X-linked juvenile retinoschisis.PMID 2032721Read ↗

Linkage relationship of X-linked juvenile retinoschisis with Xp22.1-p22.3 probes.Semantic proximity Read ↗

Linkage mapping of a large Colombian family segregating for X linked retinoschisis: refinement of the chromosomal location.Semantic proximity Read ↗

Mapping a new genetic locus for X linked retinitis pigmentosa to Xq28.Semantic proximity Read ↗

Confirmation of linkage in X-linked infantile spasms (West syndrome) and refinement of the disease locus to Xp21.3-Xp22.1.Semantic proximity Read ↗

Linkage analysis of X-linked cone-rod dystrophy: localization to Xp11.4 and definition of a locus distinct from RP2 and RP3.Semantic proximity Read ↗

Three widespread founder mutations contribute to high incidence of X-linked juvenile retinoschisis in Finland.Semantic proximity Read ↗

Confirmation and refinement of the genetic localization of the Coffin-Lowry syndrome locus in Xp22.1-p22.2.Semantic proximity Read ↗

Genetic mapping of the Kallmann syndrome and X linked ocular albinism gene loci.Semantic proximity Read ↗

A novel locus for non-syndromic sensorineural deafness (DFN6) maps to chromosome Xp22.Semantic proximity Read ↗

X-linked recessive panhypopituitarism associated with a regional duplication in Xq25-q26.Semantic proximity Read ↗

CORD9 a new locus for arCRD: mapping to 8p11, estimation of frequency, evaluation of a candidate gene.Semantic proximity Read ↗

Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.