Autosomal dominant retinitis pigmentosa: no evidence for nonallelic genetic heterogeneity on 3q.

Article

Autosomal dominant retinitis pigmentosa: no evidence for nonallelic genetic heterogeneity on 3q.

American journal of human genetics - 1 Feb 1993

Kumar-Singh R, Wang H, Humphries P, Farrar G J

Abstract excerpt

Since the initial report of linkage of autosomal dominant retinitis pigmentosa (adRP) to the long arm of chromosome 3, several mutations in the gene encoding rhodopsin, which also maps to 3q, have been reported in adRP pedigrees. However, there has been some discussion as to the possibility of a...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 3
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Genetic Variation
Humans
Lod Score
Male
Probability
Retinitis Pigmentosa
Rhodopsin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.