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Article

Susceptibility genes and overall pathogenesis of inflammatory bowel disease: where do we stand?

Digestive diseases (Basel, Switzerland) - 1 Jan 2009

Fiocchi Claudio

Abstract excerpt

The rapid accumulation of new knowledge on the genes, gene variations and genetic loci associated with both forms of inflammatory bowel disease (IBD), e.g. Crohn's disease (CD) and ulcerative colitis (UC), is shedding new light on the immunopathogenic mechanisms underlying these conditions. After the initial report of the association of NOD2 mutations with ileal CD, a large number of additional genetic variants...

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Identifiers

PMID: 19786745
DOI: 10.1159/000228554

Genes

NOD2

Provenance

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