Article
Review article: Inflammatory bowel disease and genetics.
Alimentary pharmacology & therapeutics - 1 Dec 2007
Weersma R K, van Dullemen H M, van der Steege G, Nolte I M, Kleibeuker J H, Dijkstra G
Abstract excerpt
INTRODUCTION: Inflammatory bowel disease (IBD) comprising ulcerative colitis (UC) and Crohn's disease (CD) is multigenic disorder. Tremendous progress has been achieved in unravelling the genetic background of IBD. It has led to the discovery of mutations in NOD2 associated with ileal CD and numerous other genes have been found to be associated with IBD susceptibility. METHODS: A review of the literature on the...
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