Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M <i>MAPT</i> mutations

Abstract excerpt

OBJECTIVE: To use a case-control study to assess and compare patterns of gray matter loss across groups of subjects with different mutations in the microtubule-associated protein tau (MAPT) gene. METHODS: We identified all subjects from Mayo Clinic, Rochester, Minnesota, that screened positive for mutations in MAPT and had a head MRI (n = 22). Voxel-based morphometry was used to assess patterns of gray matter...

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