Article
The PDZ2 domain of zonula occludens-1 and -2 is a phosphoinositide binding domain.
Cellular and molecular life sciences : CMLS - 1 Dec 2009
Meerschaert Kris, Tun Moe Phyu, Remue Eline, De Ganck Ariane, Boucherie Ciska, Vanloo Berlinda, Degeest Gisèle, Vandekerckhove Joël, Zimmermann Pascale, Bhardwaj Nitin, Lu Hui, Cho Wonhwa, Gettemans Jan
Abstract excerpt
Zonula occludens proteins (ZO) are postsynaptic density protein-95 discs large-zonula occludens (PDZ) domain-containing proteins that play a fundamental role in the assembly of tight junctions and establishment of cell polarity. Here, we show that the second PDZ domain of ZO-1 and ZO-2 binds phos...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
