Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease.

Neurobiology of aging - 1 Mar 2011

Turunen Mari, Vepsäläinen Saila, Mäkinen Petra, Helisalmi Seppo, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko

Abstract excerpt

High temperature requirement 1 (HTRA1) gene is a plausible risk factor in Alzheimer's disease (AD) as it encodes a protease known to degrade amyloid-β peptide. Here we have studied whether single nucleotide polymorphisms (SNPs) in the HTRA1 gene or its nearby regions associated with AD in a large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alzheimer Disease
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Europe

Share to High-Temperature Requirement A Serine Peptidase 1

Share to Kaplan-Meier Estimate

Share to Odds Ratio

Share to Serine Endopeptidases

Source

Identifiers

PMID: 19783326
DOI: 10.1016/j.neurobiolaging.2009.08.010

Genes

HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19783326-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease.PMID 19783326Read ↗

HTRA1 promoter polymorphism and risk of age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.Semantic proximity Read ↗

AMD-Associated HTRA1 Variants Do Not Influence TGF-β Signaling in Microglia.Semantic proximity Read ↗

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.Semantic proximity Read ↗

HTRA1 expression profile and activity on TGF-β signaling in HTRA1 mutation carriers.Semantic proximity Read ↗

Human HtrA1 in the archived eyes with age-related macular degeneration.Semantic proximity Read ↗

HTRA1 Variants and the Interaction with Smoking Confer the Genetic Susceptibility to Ischemic Stroke.Semantic proximity Read ↗

High-temperature requirement factor A1 rs11200638 polymorphism and age-related macular degenerative from a comprehensive analysis about 15316 subjectsSemantic proximity Read ↗

No association between CALHM1 polymorphism and Alzheimer's disease risk in a Hungarian population.Semantic proximity Read ↗

Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.Semantic proximity Read ↗

Genetic association study between alpha 1-antichymotrypsin polymorphism and Alzheimer disease in Chinese Han population.Semantic proximity Read ↗

Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.