Article
Specific clones of spontaneously evolving karyotypes generate individuality of cancers.
Cancer genetics and cytogenetics - 15 Jan 2008
Fabarius Alice, Li Ruhong, Yerganian George, Hehlmann Ruediger, Duesberg Peter
Abstract excerpt
Several researchers, including us, have recently proposed that specific karyotypes, rather than specific mutations, generate the "biochemical individuality" of cancers, defined by individual growth rates, metabolisms, drug-resistances, metastases and cell morphologies. According to our theory, in...
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