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Article

Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models.

Molecular cancer - 27 Sept 2009

Yao Qin, Qu Xun, Yang Qifeng, Good David A, Dai Shuzhen, Kong Beihua, Wei Ming Q

Abstract excerpt

BACKGROUND: Tumour stromal myofibroblasts can promote tumour invasion. As these cells are genetically more stable than cancer cells, there has been enormous interest in developing targeted molecular therapies against them. Chloride intracellular channel 4 (CLIC4) and reactive oxygen species (ROS)...

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Source

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Identifiers

PMID: 19781102
DOI: 10.1186/1476-4598-8-78
PMCID: PMC2765417

Genes

CLIC4
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19781102-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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