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Article

Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.

Neuron - 24 Sept 2009

Rajasethupathy Priyamvada, Fiumara Ferdinando, Sheridan Robert, Betel Doron, Puthanveettil Sathyanarayanan V, Russo James J, Sander Chris, Tuschl Thomas, Kandel Eric

Abstract excerpt

Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal regulation of gene expression. To explore the role of small regulatory RNAs in learning-related synaptic plasticity, we carried out massive parallel sequencing to profile the small RNAs of Aplysia californica. We identified 170 distinct miRNAs, 13 of which were novel and specific to Aplysia. Nine miRNAs were brain enriched, and...

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Identifiers

PMID: 19778509
DOI: 10.1016/j.neuron.2009.05.029
PMCID: PMC2875683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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