Article
A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Jan 2011
Till Sally M, Li Hsiu-Ling, Miniaci Maria Concetta, Kandel Eric R, Choi Yun-Beom
Abstract excerpt
Loss of the Fragile X mental retardation protein (FMRP) is associated with presumed postsynaptic deficits in mouse models of Fragile X syndrome. However, the possible presynaptic roles of FMRP in learning-related plasticity have received little attention. As a result, the mechanisms whereby FMRP...
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