Article
Immunogenotyping with antigen receptor gene probes as a diagnostic tool in childhood acute lymphoblastic leukaemia.
European journal of haematology - 1 Oct 1990
Fey M F, Tobler A, Stadelmann B, Hirt A, Theilkäs L, Khandjian E W, Ridolfi-Lüthy A, Delaleu B, Weil R, Wagner H P
Abstract excerpt
13 cases of childhood acute lymphoblastic leukaemia (ALL) were studied combining cell surface marker analysis with immunogenotyping by Southern blot hybridisation with a panel of antigen receptor gene probes. The immunophenotypes were unequivocal: 7 patients had B-phenotype and 6 patients T-phenotype ALL. In several patients immunogenotypes were not fully consistent with the respective phenotypes. For example, 2...
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