Article
Immunogenotyping with antigen receptor gene probes as a diagnostic tool in childhood acute lymphoblastic leukaemia.
European journal of haematology - 1 Oct 1990
Fey M F, Tobler A, Stadelmann B, Hirt A, Theilkäs L, Khandjian E W, Ridolfi-Lüthy A, Delaleu B, Weil R, Wagner H P
Abstract excerpt
13 cases of childhood acute lymphoblastic leukaemia (ALL) were studied combining cell surface marker analysis with immunogenotyping by Southern blot hybridisation with a panel of antigen receptor gene probes. The immunophenotypes were unequivocal: 7 patients had B-phenotype and 6 patients T-pheno...
Topics
- Adolescent
- Bacterial Proteins
- Burkitt Lymphoma
- Child
- Child, Preschool
- DNA Probes
- Deoxyribonuclease EcoRI
- Deoxyribonuclease HindIII
- Deoxyribonucleases, Type II Site-Specific
- Gene Rearrangement
- Gene Rearrangement, T-Lymphocyte
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genotype