Article
Association between polymorphisms in the FCGRT gene and lupus nephritis in Chinese patients.
Clinical and experimental rheumatology - 1 Jan 2000
Zhou X-J, Yu L, Zhu L, Hou P, Lv J-C, Yu F, Zhang H
Abstract excerpt
OBJECTIVE: Studies on mouse models have indicated that the neonatal Fc receptor (FcRn) plays important roles in a variety of autoimmune diseases. A variable number of tandem repeat (VNTR) polymorphisms within the FCGRT gene have been detected, and were found to affect the expression and functioning of FcRn. This study investigated the possible association of FCGRT VNTR polymorphisms with susceptibility and...
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