Article
Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: a common susceptibility gene in the Asian populations.
Tissue antigens - 1 Jan 2004
Chu Z T, Tsuchiya N, Kyogoku C, Ohashi J, Qian Y P, Xu S B, Mao C Z, Chu J Y, Tokunaga K
Abstract excerpt
The association of Fcgamma receptor (FcgammaR) polymorphisms with systemic lupus erythematosus (SLE) has been demonstrated in various populations; however, the results have been inconsistent. We recently identified a single-nucleotide polymorphism encoding a non-synonymous substitution, Ile232Thr (I232T), of FCGR2B and its association with SLE in Japanese and in Thais. Multiple functional FcgammaR genes with...
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