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Article

Genetic variants in FH are associated with renal histopathologic subtypes of lupus nephritis: a large cohort study from China.

Lupus - 1 Oct 2017

Tan M, Hao J-B, Chu H, Wang F-M, Song D, Zhu L, Yu F, Li Y-Z, Song Y, Zhao M-H

Abstract excerpt

Objective Genetic variants in FH (complement factor H) were reported to associate with susceptibility to systemic lupus erythematosus (SLE). This study proposed that the genetic defects of FH in the susceptibility and in the development of lupus nephritis might be different. Methods This study enrolled 334 lupus nephritis patients, 269 SLE patients without clinical renal involvement and 350 controls. Two-step...

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PMID: 28403670
DOI: 10.1177/0961203317702254

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