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Article

EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus

20 Dec 2005

Abstract excerpt

Overexpression of epidermal growth factor receptor (EGFR) is observed in many cancers, sometimes accompanied by gene amplification. Recently, several clinical therapies targeting EGFR were developed, but the eligibility criteria for these therapies is not fully established. To develop such eligibility criteria for esophageal squamous cell carcinoma (ESCC), we sought to clarify: (i) the exact frequency of EGFR...

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PMID: 16161046
DOI: 10.1002/ijc.21454

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