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Article

Latent cluster analysis of ALS phenotypes identifies prognostically differing groups.

PloS one - 22 Sept 2009

Ganesalingam Jeban, Stahl Daniel, Wijesekera Lokesh, Galtrey Clare, Shaw Christopher E, Leigh P Nigel, Al-Chalabi Ammar

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a degenerative disease predominantly affecting motor neurons and manifesting as several different phenotypes. Whether these phenotypes correspond to different underlying disease processes is unknown. We used latent cluster analysis to identify groupings of clinical variables in an objective and unbiased way to improve phenotyping for clinical and research...

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Identifiers

PMID: 19771164
DOI: 10.1371/journal.pone.0007107
PMCID: PMC2741575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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