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Article

Advances in the genetic classification of amyotrophic lateral sclerosis.

Current opinion in neurology - 1 Oct 2021

Cooper-Knock Johnathan, Harvey Calum, Zhang Sai, Moll Tobias, Timpanaro Ilia Sarah, Kenna Kevin P, Iacoangeli Alfredo, Veldink Jan H

Abstract excerpt

PURPOSE OF REVIEW: Amyotrophic lateral sclerosis (ALS) is an archetypal complex disease wherein disease risk and severity are, for the majority of patients, the product of interaction between multiple genetic and environmental factors. We are in a period of unprecedented discovery with new large-scale genome-wide association study (GWAS) and accelerating discovery of risk genes. However, much of the observed...

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Identifiers

PMID: 34343141
DOI: 10.1097/WCO.0000000000000986
PMCID: PMC7612116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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