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Article

Regional covariation and its application for predicting protein contact patches.

Proteins - 15 Feb 2010

Xu Yongbai, Tillier Elisabeth R M

Abstract excerpt

Correlated mutation analysis (CMA) is an effective approach for predicting functional and structural residue interactions from multiple sequence alignments (MSAs) of proteins. As nearby residues may also play a role in a given functional interaction, we were interested in seeing whether covarying sites were clustered, and whether this could be used to enhance the predictive power of CMA. A large-scale search for...

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PMID: 19768681
DOI: 10.1002/prot.22576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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