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Article

Pyrosequencing for SNP genotyping.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Royo Jose Luis, Galán Jose Jorge

Abstract excerpt

Pyrosequencing is a real-time DNA sequencing method. It is based on the transformation of pyrophosphates, released during DNA elongation by DNA polymerase, into measurable light. During DNA elongation, a single pyrophosphate molecule is released following incorporation of a single nucleotide. In the pyrosequencing reaction, released pyrophosphates are then rapidly converted by sulfurylase to adenosine...

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PMID: 19768590
DOI: 10.1007/978-1-60327-411-1_7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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