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Article

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer.

Oncogene - 17 Dec 2009

Mullenders J, Bernards R

Abstract excerpt

A major impediment to the effective treatment of cancer is the molecular heterogeneity of the disease, which is also reflected in an equally diverse pattern of clinical responses to therapy. Currently, only few drugs are available that can be used safely and effectively to treat cancer. To improve this situation, the development of novel and highly specific targets for therapy is of utmost importance. Possibly...

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Identifiers

PMID: 19767776
DOI: 10.1038/onc.2009.295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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