Article
RNA interference for the treatment of cancer.
Drug news & perspectives - 1 Jan 2000
Putral Lisa N, Gu Wenyi, McMillan Nigel A J
Abstract excerpt
RNA interference (RNAi) is the latest new technology in the field of genetic medicine in which specific genes can be turned off, or silenced, so as to affect a therapeutic outcome. It can be highly specific, works in the nanomolar range and is far more effective than the antisense approaches popular 10-15 years ago. Here we review the field and explore the potential role of RNAi in cancer therapy, highlighting...
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