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Article

Personalized cancer approach: using RNA interference technology.

World journal of surgery - 1 Aug 2011

Nemunaitis John, Rao Donald D, Liu Shi-He, Brunicardi F Charles

Abstract excerpt

Normal cellular survival is dependent on the cooperative expression of genes' signaling through a broad array of DNA patterns. Cancer, however, has an Achilles' heel. Its altered cellular survival is dependent on a limited subset of signals through mutated DNA, possibly as few as three. Identification and control of these signals through the use of RNA interference (RNAi) technology may provide a unique clinical...

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Identifiers

PMID: 21557010
DOI: 10.1007/s00268-011-1100-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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