Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient Adeno-associated Virus–mediated Transgenesis in Alveolar Stem Cells and Associated Niches

14 Jun 2023

Abstract excerpt

Abstract Targeted delivery of transgenes to tissue-resident stem cells and related niches offers avenues for interrogating pathways and editing endogenous alleles for therapeutic interventions. Here, we survey multiple adeno-associated virus (AAV) serotypes, administered via intranasal and retroorbital routes in mice, to target lung alveolar stem cell niches. We found that AAV5, AAV4, and AAV8 efficiently and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Interference and Gene Delivery
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37315312
DOI: 10.1165/rcmb.2022-0424ma

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient Adeno-associated Virus–mediated Transgenesis in Alveolar Stem Cells and Associated NichesPMID 37315312Read ↗

AAV-Mediated Gene Therapy for Research and Therapeutic PurposesSemantic proximity Read ↗

Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal PerspectiveSemantic proximity Read ↗

Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoidsSemantic proximity Read ↗

Population-wide gene disruption in the murine lung epithelium via AAV-mediated delivery of CRISPR-Cas9 componentsSemantic proximity Read ↗

Identification of AAV serotypes for lung gene therapy in human embryonic stem cell derived lung organoids.Semantic proximity Read ↗

Gene Therapy Using Adeno-Associated Virus VectorsSemantic proximity Read ↗

Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research ApplicationsSemantic proximity Read ↗

Adeno-associated virus vectors: versatile tools for in vivo gene transfer.Semantic proximity Read ↗

A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiencySemantic proximity Read ↗

AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airwaySemantic proximity Read ↗

An evolved AAV variant enables efficient genetic engineering of murine T cellsSemantic proximity Read ↗

Transduction of human adipose-derived mesenchymal stem cells by recombinant adeno-associated virus vectors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.