Article
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients.
Mutagenesis - 31 Dec 2020
Kroupa Michal, Rachakonda Sivaramakrishna, Vymetalkova Veronika, Tomasova Kristyna, Liska Vaclav, Vodenkova Sona, Cumova Andrea, Rossnerova Andrea, Vodickova Ludmila, Hemminki Kari, Soucek Pavel, Kumar Rajiv, Vodicka Pavel
Abstract excerpt
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been previously assessed as a potential biomarker of breast cancer (BC) risk. The present study addressed the relationship between lymphocyte TL (LTL), prognosis and clinicopathological features in the BC patients since these associations are insufficiently explored at present. LTL was measured in 611 BC patients and 154 healthy...
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