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Article

Genetic variation in telomere maintenance genes, telomere length and breast cancer risk.

PloS one - 1 Jan 2012

Shen Jing, Terry Mary Beth, Liao Yuyan, Gurvich Irina, Wang Qiao, Senie Ruby T, Santella Regina M

Abstract excerpt

BACKGROUND: Telomeres at the ends of eukaryotic chromosomes play a critical role in maintaining the integrity and stability of the genome and participate in the initiation of DNA damage/repair responses. METHODS: We performed a case-control study to evaluate the role of three SNPs (TERT-07, TERT-54 and POT1-03) in telomere maintenance genes previously found to be significantly associated with breast cancer risk....

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Identifiers

PMID: 22970196
DOI: 10.1371/journal.pone.0044308
PMCID: PMC3435409

Genes

TERT
POT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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