Article
MG-132 inhibits carcinoid growth and alters the neuroendocrine phenotype.
The Journal of surgical research - 1 Jan 2010
Chen Jui-yu, Cook Mackenzie R, Pinchot Scott N, Kunnimalaiyaan Muthusamy, Chen Herbert
Abstract excerpt
BACKGROUND: Carcinoid cancers are the most common neuroendocrine (NE) tumors, and limited treatment options exist. The inhibition of glycogen synthase kinase-3beta (GSK-3beta) has been shown to be a potential therapeutic target for the treatment of carcinoid disease. In this study, we investigate...
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