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Carbonyl cyanide 3-chlorophenylhydrazone promotes of mitophagy in gastric cancer cells MKN1 and MKN45 via PINK1/parkin pathway

2024-03-18

Abstract excerpt

BACKGROUND Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), as a common mitochondrial uncoupling agent, inducer of mitochondrial autophagy, has been used in nervous system and digestive system diseases. Mitochondrial autophagy is rarely reported in gastric cancer (GC). In this study, we used CCCP to treat MKN1 and MKN45 gastric cancer cells. METHODS We studied its effects on cell viability, migration and invasio...

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Literature Corpus work
2fd5da0e-6cf7-5535-86c7-93e873d2f293
DOI
10.21203/rs.3.rs-4099767/v1
Open publication

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Carbonyl cyanide 3-chlorophenylhydrazone promotes of mitophagy in gastric cancer cells MKN1 and MKN45 via PINK1/parkin pathwayDOI 10.21203/rs.3.rs-4099767/v1
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