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Article

Valproic acid induces Notch1 signaling in small cell lung cancer cells.

The Journal of surgical research - 1 Jul 2008

Platta Christopher S, Greenblatt David Yü, Kunnimalaiyaan Muthusamy, Chen Herbert

Abstract excerpt

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive malignancy. Current treatments yield dismal survival rates. We have previously demonstrated that histone deacetylase (HDAC) inhibitors can inhibit neuroendocrine tumor growth. Activation of the Notch1 signaling pathway also impairs SCLC c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18570928
DOI: 10.1016/j.jss.2008.03.008
PMCID: PMC2900385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18570928-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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