Article
Bone marrow derived cells in the tumour microenvironment contain cells with primitive haematopoietic phenotype.
Journal of cellular and molecular medicine - 1 Jul 2010
Deak Erika, Göttig Stephan, Rüster Brigitte, Paunescu Virgil, Seifried Erhard, Gille Jens, Henschler Reinhard
Abstract excerpt
Infiltration of bone marrow derived cells is part of the angiogenic switch required for uncontrolled tumour growth. However, the nature of the tumour-infiltrating cells from bone marrow has not been fully elucidated. To investigate the phenotype of bone marrow derived cells within a tumour, we employed the Lewis lung carcinoma (LLC) murine tumour model. We followed bone marrow derivation of tumour-infiltrating...
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