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Article

Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors.

The American journal of pathology - 1 Apr 2010

Coffelt Seth B, Lewis Claire E, Naldini Luigi, Brown J Martin, Ferrara Napoleone, De Palma Michele

Abstract excerpt

It is now established that bone marrow-derived myeloid cells regulate tumor angiogenesis. This was originally inferred from studies of human tumor biopsies in which a positive correlation was seen between the number of tumor-infiltrating myeloid cells, such as macrophages and neutrophils, and tumor microvessel density. However, unequivocal evidence was only provided once mouse models were used to examine the...

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Identifiers

PMID: 20167863
DOI: 10.2353/ajpath.2010.090786
PMCID: PMC2843445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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