Article
Systemic inhibition of tumour angiogenesis by endothelial cell-based gene therapy.
British journal of cancer - 20 Aug 2007
Dudek A Z, Bodempudi V, Welsh B W, Jasinski P, Griffin R J, Milbauer L, Hebbel R P
Abstract excerpt
Angiogenesis and post-natal vasculogenesis are two processes involved in the formation of new vessels, and both are essential for tumour growth and metastases. We isolated endothelial cells from human blood mononuclear cells by selective culture. These blood outgrowth cells expressed endothelial cell markers and responded correctly to functional assays. To evaluate the potential of blood outgrowth endothelial...
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