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Article

Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways.

PLoS pathogens - 1 Sept 2009

Rong Rong, Li Bing, Lynch Rebecca M, Haaland Richard E, Murphy Megan K, Mulenga Joseph, Allen Susan A, Pinter Abraham, Shaw George M, Hunter Eric, Robinson James E, Gnanakaran S, Derdeyn Cynthia A

Abstract excerpt

One aim for an HIV vaccine is to elicit neutralizing antibodies (Nab) that can limit replication of genetically diverse viruses and prevent establishment of a new infection. Thus, identifying the strengths and weaknesses of Nab during the early stages of natural infection could prove useful in achieving this goal. Here we demonstrate that viral escape readily occurred despite the development of high titer...

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Share to Acute Disease
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antibody Diversity

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Share to HIV Envelope Protein gp120

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Source

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Identifiers

PMID: 19763269
DOI: 10.1371/journal.ppat.1000594
PMCID: PMC2741593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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