Article
RelA regulates virulence and intracellular survival of Francisella novicida.
Microbiology (Reading, England) - 1 Dec 2009
Dean R E, Ireland P M, Jordan J E, Titball R W, Oyston P C F
Abstract excerpt
Analysis of the genome of Francisella tularensis has revealed few regulatory systems, and how the organism adapts to conditions in different niches is poorly understood. The stringent response is a global stress response mediated by (p)ppGpp. The enzyme RelA has been shown to be involved in generation of this signal molecule in a range of bacterial species. We investigated the effect of inactivation of the relA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
