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Article

Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes.

Infection and immunity - 1 Jul 2007

Mohapatra Nrusingh P, Soni Shilpa, Bell Brian L, Warren Richard, Ernst Robert K, Muszynski Artur, Carlson Russell W, Gunn John S

Abstract excerpt

Francisella tularensis is a category A agent of biowarfare/biodefense. Little is known about the regulation of virulence gene expression in Francisella spp. Comparatively few regulatory factors exist in Francisella, including those belonging to two-component systems (TCS). However, orphan members of typical TCS can be identified. To determine if orphan TCS members affect Francisella gene expression, a gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17452468
DOI: 10.1128/IAI.00351-07
PMCID: PMC1932945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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