Article
Regression-based approach for testing the association between multi-region haplotype configuration and complex trait.
BMC genetics - 17 Sept 2009
Hu Yanling, Jason Sinnwell, Wang Qishan, Pan Yuchun, Zhang Xiangzhe, Zhao Hongbo, Li Changlong, Sun Libin
Abstract excerpt
BACKGROUND: It is quite common that the genetic architecture of complex traits involves many genes and their interactions. Therefore, dealing with multiple unlinked genomic regions simultaneously is desirable. RESULTS: In this paper we develop a regression-based approach to assess the interactions of haplotypes that belong to different unlinked regions, and we use score statistics to test the null hypothesis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
