Article
Rapid screening for phenotype-genotype associations by linear transformations of genomic evaluations.
BMC bioinformatics - 19 Jul 2014
Gualdrón Duarte Jose L, Cantet Rodolfo J C, Bates Ronald O, Ernst Catherine W, Raney Nancy E, Steibel Juan P
Abstract excerpt
BACKGROUND: Currently, association studies are analysed using statistical mixed models, with marker effects estimated by a linear transformation of genomic breeding values. The variances of marker effects are needed when performing the tests of association. However, approaches used to estimate the parameters rely on a prior variance or on a constant estimate of the additive variance. Alternatively, we propose a...
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