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Article

Comparison of two multi-trait association testing methods and sequence-based fine mapping of six additive QTL in Swiss Large White pigs.

BMC genomics - 10 Apr 2023

Nosková A, Mehrotra A, Kadri N K, Lloret-Villas A, Neuenschwander S, Hofer A, Pausch H

Abstract excerpt

BACKGROUND: Genetic correlations between complex traits suggest that pleiotropic variants contribute to trait variation. Genome-wide association studies (GWAS) aim to uncover the genetic underpinnings of traits. Multivariate association testing and the meta-analysis of summary statistics from single-trait GWAS enable detecting variants associated with multiple phenotypes. In this study, we used array-derived...

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PMID: 37038103
DOI: 10.1186/s12864-023-09295-4
PMCID: PMC10084639

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