Article
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.
Nature - 10 Jul 2008
Neumüller Ralph A, Betschinger Joerg, Fischer Anja, Bushati Natascha, Poernbacher Ingrid, Mechtler Karl, Cohen Stephen M, Knoblich Juergen A
Abstract excerpt
Drosophila neuroblasts and ovarian stem cells are well characterized models for stem cell biology. In both cell types, one daughter cell self-renews continuously while the other undergoes a limited number of divisions, stops to proliferate mitotically and differentiates. Whereas neuroblasts segregate the Trim-NHL (tripartite motif and Ncl-1, HT2A and Lin-41 domain)-containing protein Brain tumour (Brat) into one...
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