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Article

Role of interferon-gamma gene polymorphisms in susceptibility to IgA nephropathy: a family-based association study.

European journal of human genetics : EJHG - 1 Apr 2006

Schena Francesco Paolo, Cerullo Giuseppina, Torres Diletta Domenica, Scolari Francesco, Foramitti Marina, Amoroso Antonio, Pirulli Doroti, Floege Jürgen, Mertens Peter Rene, Zerres Klaus, Alexopoulos Efstathios, Kirmizis Dimitrios, Zelante Leopoldo, Bisceglia Luigi

Abstract excerpt

T helper (h) lymphocytes in pathogenic immune response at mucosal effector site play a key role in IgA nephropathy (IgAN). We evaluated the impact of some Th1/Th2/Th3/T(R)-type, and of monocyte/macrophage cytokines on IgAN susceptibility with a family-based association study including 53 patients, 45 complete trios, 4 incomplete trios and 36 discordant siblings. Cytokine gene polymorphisms with a potential...

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Identifiers

PMID: 16493441
DOI: 10.1038/sj.ejhg.5201591

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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