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Article

The role of lysophosphatidic acid receptors in phenotypic modulation of vascular smooth muscle cells.

Molecular biology reports - 1 Jul 2010

Zhou Zhibin, Niu Jianping, Zhang Zhijun

Abstract excerpt

Lysophosphatidic acid (LPA) is a bioactive lipid with diverse physiological effects via activation of G protein-coupled receptors (GPCRs). It has been implicated as a specific dedifferentiation factors that can promote phenotypic modulation of cultured vascular smooth muscle cells (VSMCs) which is critically involved in various vascular disease. However, the role of LPA receptors and details of their signaling in...

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Source

Identifiers

PMID: 19757175
DOI: 10.1007/s11033-009-9798-6

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of lysophosphatidic acid receptors in phenotypic modulation of vascular smooth muscle cells.PMID 19757175Read ↗

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Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro.Semantic proximity Read ↗

[Current progress of phenotypic modulation of vascular smooth muscle cells].Semantic proximity Read ↗

Cell surface receptors in lysophospholipid signaling.Semantic proximity Read ↗

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Asprosin aggravates atherosclerosis via regulating the phenotype transformation of vascular smooth muscle cells.Semantic proximity Read ↗

[Phenotypic modulation of vascular smooth muscle cells in diabetes mellitus and intervention of traditional Chinese medicines].Semantic proximity Read ↗

Impaired peroxisome proliferator-activated receptor-gamma contributes to phenotypic modulation of vascular smooth muscle cells during hypertension.Semantic proximity Read ↗

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