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Article

Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg.

Cell and tissue research - 1 Nov 2009

Dey Bijan Kumar, Zhao Xiao-Li, Popo-Ola Emmanuel, Campos Ana Regina

Abstract excerpt

The Drosophila disconnected (disco) gene encodes a C(2)H(2)-type zinc finger transcription factor required for the development of the central and peripheral nervous systems. We report that disco participates in a positive feedback loop with the Dll gene, a master regulator of ventral appendage development. Dll function is not only required for proper disco expression in antenna and leg discs, but is also...

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PMID: 19756755
DOI: 10.1007/s00441-009-0865-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg.PMID 19756755Read ↗

Isolation and characterization of the disconnected gene of Drosophila melanogaster.Semantic proximity Read ↗

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The Drosophila genes disconnected and disco-related are redundant with respect to larval head development and accumulation of mRNAs from deformed target genes.Semantic proximity Read ↗

The Drosophila gap gene giant has an anterior segment identity function mediated through disconnected and teashirt.Semantic proximity Read ↗

Behavioral and molecular analyses suggest that circadian output is disrupted by disconnected mutants in D. melanogaster.Semantic proximity Read ↗

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Control of the spineless antennal enhancer: direct repression of antennal target genes by Antennapedia.Semantic proximity Read ↗

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