Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg.

doi:10.1007/s00441-009-0865-z

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Article

Mutual regulation of the Drosophila disconnected (disco) and Distal-less (Dll) genes contributes to proximal-distal patterning of antenna and leg.

Cell and tissue research - 1 Nov 2009

Dey Bijan Kumar, Zhao Xiao-Li, Popo-Ola Emmanuel, Campos Ana Regina

Abstract excerpt

The Drosophila disconnected (disco) gene encodes a C(2)H(2)-type zinc finger transcription factor required for the development of the central and peripheral nervous systems. We report that disco participates in a positive feedback loop with the Dll gene, a master regulator of ventral appendage de...

Topics

Alleles
Animals
Body Patterning
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Extremities
Gene Expression Regulation, Developmental
Genes, Insect
Homeodomain Proteins
Phenotype
Retina
Transcription Factors
Wings, Animal

Source

Open in PubMed

Identifiers

PMID: 19756755
DOI: 10.1007/s00441-009-0865-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19756755-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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