Article
The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998
Zeng C, Justice N J, Abdelilah S, Chan Y M, Jan L Y, Jan Y N
Abstract excerpt
The process of wing patterning involves precise molecular mechanisms to establish an organizing center at the dorsal-ventral boundary, which functions to direct the development of the Drosophila wing. We report that misexpression of dLMO, a Drosophila LIM-only protein, in specific patterns in the developing wing imaginal disc, disrupts the dorsal-ventral (D-V) boundary and causes errors in wing patterning. When...
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